District Ghotki has its due importance as the city hosts both the industrial and agricultural zones. It is the second most revenue generating city of the provinces Sindh. The land of Ghotki is very fertile and produces various crops including Cotton, Wheat, Sugarcane and Rice. The industrial zone of Ghotki plays a vital role in the revenue generation of District Ghotki and contributes towards a big chum of the province Sindh. The main role players in the industrial section of Ghotki are some big names from the corporate sector of Pakistan including Oil and Gas Company Limited (OGDCL), Engro chemicals, Fauji Fertilizers, Liberty Power and others industries northern Sindh, Pakistan; According to the 1998 census it had a population of 970,549. Mirpur Mathelo is the capital city of Ghotki district. District Ghotki borders tourches Kot Sabzal and Sanjarpur towns of Punjab province.

The town is located at 28 1’ ON 69 19’OE with an altitude of 72 metres (239 ft). Ghotki has generally moderately hot weather around the year and the winter lasts for 3 months per calendar year. Like other cities of Sindh, district Ghotki also has its deep rooted cultural values. Ghotki was founded by a statemen of Raja Ibn Selaj Birhman (a relative of Raja Dahar of Sindh) in 637 A.D (15th year of Hijra) named Hath Sam who set up an army settlement/camp after defeating a Muslim Army of Arabia. The camp later assumed the shape of a village on 17th Shaban in 17th year of Hijra (369 A.D) when people of different tribes came to settle here. Two years later, the people deserted this village and it again became a land of birds and animals. In year 695 A.D, certain fishermen came here and settled and named the village as “Miani” but when the river changed its course the people left the village again to the mercy of jackals. The history claims that Islam entered subcontinent from Sindh and Jamia Mosque in Ghotki is over 300 years old which is also the evidence that proves Sindh served as a gateway for Islam in subcontinent.